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Clayman added, "We believe that Zilretta has the potential to be a transformative medicine for the more than five million patients who receive an intra-articular injection for OA knee pain each year." The FDA approval of Zilretta is based upon data from Flexion's pivotal Phase 3 clinical trial.
The randomized, double-blind study enrolled 484 patients at 37 centers worldwide. D., Co-Director, Joint Replacement Program, Cedars-Sinai Orthopaedic Center, said, "OA knee pain presents a host of challenges for patients and clinicians alike, and there has been very little innovation in this area in recent years.
In 2004, Murray starred in the romantic comedy A Cinderella Story with Hilary Duff. Though most film critics gave the film negative reviews, House of Wax earned over ,766,121 worldwide.
Though the reviews were mostly negative, the film went on to become a moderate box office success, earning .1 million worldwide. The film led to Murray receiving the 2005 Teen Choice Awards win category for "Choice Movie Actor: Action/Adventure/Thriller".
He is known for portraying Lucas Scott in The WB/CW drama series One Tree Hill from 2003 to 2009, and for his portrayal of war veteran and SSR agent Jack Thompson in the Marvel/ABC series Agent Carter.
However, Mark Schwann said in an interview that he had been offered "great things" to return to the show. In 2013, Murray appeared in Fruitvale Station, a film chronicling the last day of Oscar Grant, who was killed by a police officer at a BART station.
The film won two major awards at the 2013 Sundance Film Festival.
The film was a major box office success, earning a total of 0,222,438 in the United States alone.
Critics were mostly positive in their reviews of the film, and the film garnered a "B" grade on Yahoo!